"Religion can be the enemy of God. It's often what happens when God, like Elvis, has left the building. A list of instructions where there was once conviction; dogma where once people just did it; a congregation led by a man where once they were led by the Holy Spirit. Discipline replacing discipleship."
As with a lot of Bono quotes, I tend to think that his words need no explanation. Simply: This is not to say that organization of faith or belief (formal church) cannot work, only that it becomes dangerous where it becomes more about the institution and less about the faith itself.